I have been busy looking into more obvious causes of 'Inflammation' and its causes, and surprise most of that might come from our eating habits.
There is an argument that up to 25% of humanity suffers from what is known as 'Metabolic Syndrome' (METS), and that it is a precursor of a diagnosis in Diabetes, and other related Cardio' vascular problems.
So what is METS?
Here is a small You Tube I found to try to help explain the condition, and what to be looking out for:
The Reference below has an article that has a Movie File attached to the document and to the Study that this story / article refers to.
It is worth noting that this article points to a small cohort Pilot Study, that indicates 'Time Restricted Eating' (TRE), will help reduce body weight and waist circumference without actually having to add an Exercise regime, and for many of us, we are older and more sedentary because of our ages... Hence, a dietary plan such as this might really help us in so many ways, in my view...
Best wishes
Steve
ABSTRACT
Summary
In animal models, time-restricted feeding (TRF) can prevent and reverse aspects of metabolic diseases. Time-restricted eating (TRE) in human pilot studies reduces the risks of metabolic diseases in otherwise healthy individuals. However, patients with diagnosed metabolic syndrome often undergo pharmacotherapy, and it has never been tested whether TRE can act synergistically with pharmacotherapy in animal models or humans. In a single-arm, paired-sample trial, 19 participants with metabolic syndrome and a baseline mean daily eating window of ≥14 h, the majority of whom were on a statin and/or antihypertensive therapy, underwent 10 h of TRE (all dietary intake within a consistent self-selected 10 h window) for 12 weeks. We found this TRE intervention improves cardiometabolic health for patients with metabolic syndrome receiving standard medical care including high rates of statin and anti-hypertensive use. TRE is a potentially powerful lifestyle intervention that can be added to standard medical practice to treat metabolic syndrome.
DIRECT LINK TO ARTICLE & SHORT FILM CLIP EMBEDDED IN ARTICLE ON METS:
https://www.sciencedirect.com/science/a ... via%3Dihub
CONCLUSION
To our knowledge, this is a unique study of TRE in humans who have metabolic syndrome. The high level of adherence to TRE in our study, no reported adverse effects, and low dropout rate suggest that a self-selected 10 h window for TRE may be feasible for patients with metabolic syndrome to adhere to over a longer period of time. The use of a smartphone application to capture real-time data about meal timing and sleep restfulness is a unique tool to monitor and intervene in the circadian aspects of lifestyle and its day-to-day variance. The use of this smartphone app will allow us to design larger studies of TRE in which participants are monitored remotely over even longer periods of time.
This study has demonstrated that a 10 h TRE intervention over 12 weeks, without an overt attempt to change physical activity or diet quality or quantity, can serve as a novel treatment for individuals with metabolic syndrome. Importantly, we observed significant decreases in systolic and diastolic blood pressure, total cholesterol, LDL-C, and non-HDL-C. These findings occurred without increased physical activity, and there was no significant correlation with changes in weight (Table S3). However, a decrease in waist circumference was correlated with change in weight (p = 0.017), a larger correlation with decreased eating interval (p = 0.005), and a combined change in weight and eating interval (p = 0.004) (Table S3). Most participants were already taking stable doses of cardiovascular medications (79% and 63% of patients were taking a statin and anti-hypertensive therapy, respectively; Table S2), suggesting that the observed benefits of TRE were additive to the effects of these medications. Among participants with elevated fasting blood glucose and/or HbA1c, we also observed a significant reduction in HbA1c. In this population at high risk for CVD, a significant reduction in atherogenic lipids, blood pressure, and blood glucose on top of medical therapy has important clinical implications.
REFERENCE
Wilkinson et al. 2019. "Cell Metabolism: "Ten-hour time-restricted eating reduces weight, blood pressure, and atherogenic lipids in patients with metabolic syndrome" https://www.cell.com/cell-metabolism/fu ... 19)30611-4 , DOI: 10.1016/j.cmet.2019.11.004