MATEs FORUM

Update: Bomedemstat as effective medication for ET....
Bomedemstat has been designated as an orphan drug for ET by the EMA in Europe.

https://www.youtube.com/watch?v=JZH8JI5BejI
https://www.ema.europa.eu/en/medicines/ ... -3-21-2451

Evening all... :-) Below is a most exciting Update from Prof. Daniel Thomas concerning the imminent CALR "Monoclonal" antibodies, and he also goes on to mention further interesting events concerning JAK2 & CMML. Anyways, all very welcome and potentially "ground-breaking news"...

Hello fellow warriors...I am wondering if any MPNérs have experience using Isoquercitrin ? This is a powerful natural LSD1 inhibitor from Quercetin. Of has been several research done with LSD1 inhibitors and MPN, one example is Bomedemstat. Greetings Paul Netherlands

Thanks Steve … of course thanks!! hopefully everything is fine there.. Maybe after 40 years we'll finally get rid of current horse tools.... Greetings Paul

Hi David, is there already a publication on the mutated JAK2 without targeting normal cells (upcoming publication in Blood Cancer Discovery) ?
I can't find it yet... Greetings Paul